Eva Frei Selected Research

1-phenylazo-2-naphthol (Sudan I)

1/2014	Enzymes oxidizing the azo dye 1-phenylazo-2-naphthol (Sudan I) and their contribution to its genotoxicity and carcinogenicity.
2/2013	Induced expression of cytochrome P450 1A and NAD(P)H:quinone oxidoreductase determined at mRNA, protein, and enzyme activity levels in rats exposed to the carcinogenic azo dye 1-phenylazo-2-naphthol (Sudan I).
9/2009	Oxidation of the carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxy-naphthalene (Sudan I) by cytochromes P450 and peroxidases: a comparative study.

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Eva Frei Research Topics

Disease

47	Neoplasms (Cancer) 01/2020 - 04/2002
15	Balkan Nephropathy (Balkan Endemic Nephropathy) 01/2017 - 01/2008
7	Neuroblastoma 01/2018 - 05/2009
6	Body Weight (Weight, Body) 02/2011 - 08/2006
3	Colorectal Neoplasms (Colorectal Cancer) 01/2020 - 01/2015
3	Inflammation (Inflammations) 08/2015 - 08/2010
3	Leukemia 01/2015 - 07/2007
3	Brain Neoplasms (Brain Tumor) 05/2011 - 01/2009
3	Fibrosis (Cirrhosis) 03/2009 - 06/2008
3	Chronic Kidney Failure (Chronic Renal Failure) 03/2009 - 06/2008
2	Colonic Neoplasms (Colon Cancer) 01/2020 - 12/2011
2	Melanoma (Melanoma, Malignant) 01/2012 - 02/2005
2	Glioblastoma (Glioblastoma Multiforme) 06/2011 - 01/2009
2	Carcinogenesis 02/2011 - 01/2007
1	Rectal Neoplasms (Rectal Cancer) 01/2020
1	Neoplasm Metastasis (Metastasis) 01/2016
1	Carcinoma (Carcinomatosis) 11/2015
1	Pneumonia (Pneumonitis) 08/2015
1	Adenocarcinoma 06/2011
1	Prostatic Neoplasms (Prostate Cancer) 10/2010
1	Glioma (Gliomas) 03/2009

Drug/Important Bio-Agent (IBA)

24	aristolochic acid I (aristolochic acid)IBA 01/2017 - 04/2002
19	ellipticineIBA 01/2018 - 12/2005
17	DNA AdductsIBA 01/2015 - 07/2002
15	Pharmaceutical PreparationsIBA 01/2020 - 07/2002
15	EnzymesIBA 01/2020 - 01/2008
11	CarcinogensIBA 11/2015 - 04/2002
10	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 01/2007
4	Antineoplastic Agents (Antineoplastics)IBA 01/2014 - 01/2009
4	AlbuminsIBA 06/2011 - 08/2006
3	Cytochrome P-450 CYP3AIBA 01/2020 - 01/2011
3	Biological ProductsIBA 01/2020 - 01/2007
3	Histone Deacetylase InhibitorsIBA 01/2018 - 06/2010
3	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 08/2015 - 01/2011
3	1-phenylazo-2-naphthol (Sudan I)IBA 01/2014 - 09/2009
2	XenobioticsIBA 01/2020 - 05/2015
2	Valproic Acid (Depakote)FDA LinkGeneric 01/2018 - 01/2011
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2018 - 06/2010
2	AlkaloidsIBA 02/2016 - 10/2008
2	Biomarkers (Surrogate Marker)IBA 01/2015 - 01/2007
2	Cytochromes b5 (Cytochrome b5)IBA 12/2014 - 01/2011
2	Plant ExtractsIBA 05/2014 - 01/2014
2	Peroxidase (Myeloperoxidase)IBA 01/2014 - 06/2011
2	2-anisidine (o-anisidine)IBA 06/2012 - 03/2009
2	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2012 - 06/2010
2	Environmental Pollutants (Pollutants, Environmental)IBA 06/2012 - 03/2009
2	12-hydroxyellipticineIBA 06/2011 - 07/2007
2	Human Serum Albumin FDA LinkGeneric 05/2011 - 03/2009
2	5-aminofluoresceinIBA 05/2011 - 03/2009
2	PeroxidasesIBA 01/2011 - 12/2005
2	MutagensIBA 09/2009 - 03/2009
2	Fibronectins (Fibronectin)IBA 02/2008 - 02/2005
1	UGT1A8 UDP-glucuronosyltransferase (UGT1A8)IBA 01/2020
1	Cytochrome P-450 CYP2C9IBA 01/2020
1	bilirubin uridine-diphosphoglucuronosyl transferase 1A10 (UGT1A10)IBA 01/2020
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	Cytostatic AgentsIBA 01/2016
1	MetalsIBA 01/2016
1	PlatinumIBA 01/2016
1	Adenosine Triphosphatases (ATPase)IBA 09/2015
1	Chloroquine (Aralen)FDA LinkGeneric 09/2015
1	Vacuolar Proton-Translocating ATPases (V-Type ATPase)IBA 09/2015
1	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 08/2015
1	Air Pollutants (Pollutants, Air)IBA 08/2015
1	Benzo(a)pyreneIBA 08/2015
1	LipopolysaccharidesIBA 08/2015
1	Ethylene Oxide (Oxirane)IBA 01/2015
1	allyl glycidyl etherIBA 01/2015
1	Cytotoxins (Cytolysins)IBA 01/2015
1	MicellesIBA 01/2015
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2014
1	EllipticinesIBA 01/2014
1	Type II DNA Topoisomerases (Topoisomerase II)IBA 01/2014
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2014
1	Environmental CarcinogensIBA 02/2013
1	Azo CompoundsIBA 02/2013
1	Formaldehyde (Formol)FDA Link 06/2012
1	Extracellular Matrix ProteinsIBA 01/2012
1	furanIBA 01/2012
1	OligosaccharidesIBA 01/2012
1	HydrogenIBA 01/2012
1	Sulfates (Sulfates, Inorganic)IBA 01/2012
1	Galactose (Galactopyranose)FDA LinkGeneric 01/2012
1	2- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA 12/2011
1	benzocycloheptapyridineIBA 12/2011
1	LigandsIBA 06/2011
1	Coloring Agents (Dyes)IBA 05/2011
1	FlavonoidsIBA 01/2011
1	theasinensin AIBA 01/2011
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2011
1	trichostatin A (A 300)IBA 01/2011
1	Drug CarriersIBA 08/2010
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 06/2010
1	Etoposide (VP 16)FDA LinkGeneric 06/2010
1	Coenzymes (Enzyme Cofactors)IBA 05/2009
1	Messenger RNA (mRNA)IBA 05/2009
1	Proteins (Proteins, Gene)FDA Link 05/2009
1	AminesIBA 03/2009

Therapy/Procedure

2	Therapeutics 09/2015 - 06/2010